How far is Greenwood, MS from Biloxi, MS?
The driving distance from Greenwood, MS to Biloxi, MS is about 262.4 miles (422.3 km), with a travel time of about 04h 29m by car.
- The straight-line flight distance is about 228.5 miles (367.8 km).
- For a round trip, plan for roughly 08h 58m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 29m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Mississippi
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Greenwood and Biloxi.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenwood and Biloxi.
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1
Start on Main Street
1.1 mi · 2 min · Main Street
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2
Continue straight
23.7 mi · 35 min
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3
Continue straight
11.1 mi · 16 min
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4
Turn slight right
149 m · 9 sec
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5
Turn right onto Yazoo Street
2376 ft · 42 sec · Yazoo Street
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6
Continue on MS 17
12.7 mi · 19 min · MS 17
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7
Take the ramp right
1661 ft · 41 sec
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8
Merge slight left
48.8 mi · 54 min
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9
Take the exit slight right toward I 20 East, US 49 South: Meridian, Hattiesburg
1.5 km · 1 min
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10
Keep slight right to continue on Richland, Hattiesburg
1.2 km · 2 min
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11
Merge slight left onto Highway 49 South
80.3 mi · 1 hr 37 min · Highway 49 South
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12
Continue straight
2294 ft · 36 sec
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13
Continue straight
1.1 mi · 2 min
-
14
Take the exit slight right toward I 59 South: New Orleans, Gulf Coast
1914 ft · 36 sec
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15
Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway
7.7 mi · 8 min · Lance Corporal Roy M Wheat Memorial Highway
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16
Take the exit slight right toward US 98 East: Lucedale, Mobile
3.2 mi · 4 min
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17
Take the exit slight right toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
1558 ft · 44 sec
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18
Keep slight left to continue on Multi Purpose Center, Hattiesburg
833 ft · 28 sec
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19
Turn right
41.9 mi · 49 min
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20
Take the exit slight right toward MS 67 South: D'Iberville, Biloxi
1.2 km · 1 min
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21
Continue on Biloxi-D'Iberville Scenic Expressway
20.5 mi · 24 min · Biloxi-D'Iberville Scenic Expressway
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22
Continue straight
3.2 mi · 4 min
-
23
Take the exit slight right toward Division Street
1852 ft · 47 sec
-
24
Turn left onto Division Street
3090 ft · 2 min · Division Street
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25
Turn right onto Main Street
2572 ft · 1 min · Main Street
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26
Turn left onto Howard Avenue
28 m · 3 sec · Howard Avenue
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27
Arrive at your destination
0 m · 1 sec · Howard Avenue
Car Route Details
A richer read on the saved driving route between Greenwood and Biloxi.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Highway 49 South
Merge slight left onto Highway 49 South
80.3 mi · 01h 37m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Greenwood and Sunny near Biloxi.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenwood to Biloxi?
The road trip is about 262.4 miles (422.3 km) and usually takes 04h 29m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Mendenhall is a useful midpoint, sitting about 130.7 miles from Greenwood and 131.7 miles from Biloxi.
How much longer is the road route than the straight-line distance?
The direct path is about 228.5 miles (367.8 km), while the road route adds roughly 33.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:02 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.07 one way or $70.14 round trip. Estimated CO2 is about 82.3 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Greenwood and Sunny near Biloxi.
Stop Ideas Near Mendenhall
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Mendenhall.
Union Station
Hazlehurst station
Brookhaven
Laurel station
Flight Path Map
This map shows the direct air route between Greenwood and Biloxi. Straight-line distance: 228.54 mi (367.8 km).
#1 Greenwood
Greenwood is a place in Mississippi, United States.
| Population | 0 |
| Coordinates | 33.5162300, -90.1795300 |
| Altitude | 40 |
| Country | United States |
#2 Biloxi
The most populous city in Harrison County, Mississippi.
| Population | 46,127 |
| Coordinates | 30.3960300, -88.8853100 |
| Altitude | 6 |
| Country | United States |
End: Howard Avenue (-88.885301, 30.396075)
Estimated Travel Time
Distance: 422 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 44m |
| 40 mph (64.37 km/h) | 06h 33m |
| 50 mph (80.47 km/h) | 05h 14m |
| 60 mph (96.56 km/h) | 04h 22m |
| 70 mph (112.65 km/h) | 03h 44m |
| 80 mph (129 km/h) | 03h 16m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $35.07 | $70.14 |
| Mid-grade | $4.26 | $39.44 | $78.88 |
| Premium | $4.63 | $42.83 | $85.66 |
| Diesel | $5.42 | $50.14 | $100.29 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.