How far is Greenville, MS from Vancleave, MS?
The driving distance from Greenville, MS to Vancleave, MS is about 298 miles (479.6 km), with a travel time of about 06h 06m by car.
- The straight-line flight distance is about 242.1 miles (389.6 km).
- For a round trip, plan for roughly 12h 13m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 06m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Simpson County, Mississippi, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Cloudy
Driving Route Map
The map below follows the saved road route between Greenville and Vancleave.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville and Vancleave.
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1
Start on South Broadway Street
3 m · 8 sec · South Broadway Street
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2
Turn left onto Main Street
1.4 km · 2 min · Main Street
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3
Turn left
9.2 mi · 14 min
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4
Turn left
15.8 mi · 19 min
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5
Turn right onto North Martin Luther King Drive
46.2 mi · 56 min · North Martin Luther King Drive
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6
Keep slight right to continue on US 49 South: Jackson
2791 ft · 53 sec
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7
Merge slight right onto Jerry Clower Boulevard
38.8 mi · 48 min · Jerry Clower Boulevard
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8
Take the exit slight right
4.9 mi · 6 min
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9
Keep slight left
3.8 mi · 5 min
-
10
Merge slight right
1.1 mi · 1 min
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11
Keep slight right to continue on Meridian, Hattiesburg
106 m · 5 sec
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12
Take the exit slight right toward Hattiesburg
2977 ft · 42 sec
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13
Keep slight right to continue on Richland, Hattiesburg
1.2 km · 2 min
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14
Merge slight left onto Highway 49 South
80.3 mi · 1 hr 37 min · Highway 49 South
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15
Continue straight
2294 ft · 36 sec
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16
Continue straight
1.1 mi · 2 min
-
17
Take the exit slight right toward I 59 South: New Orleans, Gulf Coast
1914 ft · 36 sec
-
18
Merge slight left onto Lance Corporal Roy M Wheat Memorial Highway
7.7 mi · 8 min · Lance Corporal Roy M Wheat Memorial Highway
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19
Take the exit slight right toward US 98 East: Lucedale, Mobile
3.2 mi · 4 min
-
20
Take the exit slight right toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
1558 ft · 44 sec
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21
Keep slight left to continue on Multi Purpose Center, Hattiesburg
833 ft · 28 sec
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22
Turn right
41.9 mi · 49 min
-
23
Take the exit slight right toward MS 67 South: D'Iberville, Biloxi
1.2 km · 1 min
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24
Continue on Biloxi-D'Iberville Scenic Expressway
20.5 mi · 24 min · Biloxi-D'Iberville Scenic Expressway
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25
Continue straight
672 ft · 11 sec
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26
Take the exit slight right toward I 10 East: Pascagoula, Mobile
1715 ft · 47 sec
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27
Keep slight left to continue on I 10
1284 ft · 31 sec
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28
Merge slight left
10.4 mi · 11 min
-
29
Take the exit slight right toward MS 57: Vancleave, Gautier, Ocean Springs
1306 ft · 32 sec
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30
Keep slight left
28 m · 4 sec
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31
Turn left
7.5 mi · 11 min
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32
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Greenville and Vancleave.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Highway 49 South
Merge slight left onto Highway 49 South
80.3 mi · 01h 37m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Partly Cloudy leaving Greenville and Sunny near Vancleave.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenville to Vancleave?
The road trip is about 298 miles (479.6 km) and usually takes 06h 06m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
D'Lo is a useful midpoint, sitting about 149.2 miles from Greenville and 148.9 miles from Vancleave.
How much longer is the road route than the straight-line distance?
The direct path is about 242.1 miles (389.6 km), while the road route adds roughly 55.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $39.84 one way or $79.68 round trip. Estimated CO2 is about 93.5 kg one way.
What should you check before leaving?
Before you leave, expect Partly Cloudy around Greenville and Sunny near Vancleave.
Stop Ideas Near D'Lo
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to D'Lo.
Union Station
Hazlehurst station
Brookhaven
Laurel station
Flight Path Map
This map shows the direct air route between Greenville and Vancleave. Straight-line distance: 242.08 mi (389.59 km).
#1 Greenville
City in Washington County, Mississippi, United States
| Population | 28,315 |
| Coordinates | 33.4089800, -91.0597800 |
| Altitude | 40 |
| Country | United States |
#2 Vancleave
Census-designated place in Jackson County, Mississippi
| Population | 5,886 |
| Coordinates | 30.5404700, -88.6875200 |
| Altitude | 9 |
| Country | United States |
End: Vancleave (-88.68752, 30.54047)
Estimated Travel Time
Distance: 480 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 55m |
| 40 mph (64.37 km/h) | 07h 27m |
| 50 mph (80.47 km/h) | 05h 57m |
| 60 mph (96.56 km/h) | 04h 58m |
| 70 mph (112.65 km/h) | 04h 15m |
| 80 mph (129 km/h) | 03h 43m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $39.84 | $79.68 |
| Mid-grade | $4.26 | $44.80 | $89.61 |
| Premium | $4.63 | $48.66 | $97.31 |
| Diesel | $5.42 | $56.97 | $113.93 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · Apr 16, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.