How far is Greeneville, TN from Winston-Salem, NC?
The driving distance from Greeneville, TN to Winston-Salem, NC is about 204.4 miles (328.9 km), with a travel time of about 03h 57m by car.
- The straight-line flight distance is about 144.4 miles (232.4 km).
- For a round trip, plan for roughly 07h 55m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 57m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town of the United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Greeneville and Winston-Salem.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greeneville and Winston-Salem.
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1
Start on South Main Street
1.2 mi · 3 min · South Main Street
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2
Turn right onto East Andrew Johnson Highway
159 m · 14 sec · East Andrew Johnson Highway
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3
Turn left onto Kingsport Highway
19.3 mi · 29 min · Kingsport Highway
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4
Turn left
1.2 mi · 2 min
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5
Continue straight
793 ft · 13 sec
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6
Take the ramp slight right
2129 ft · 52 sec
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7
Merge slight left
106.3 mi · 1 hr 54 min
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8
Keep slight right to continue on I 77 South: Charlotte North Carolina
23.5 mi · 27 min
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9
Take the exit slight right toward VA 148, SR 775: Fancy Gap
1381 ft · 36 sec
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10
Turn straight onto Chance Creek Road
1.4 km · 1 min · Chance Creek Road
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11
At the end of the road, turn right onto Fancy Gap Highway
9.4 mi · 11 min · Fancy Gap Highway
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12
Continue on North Andy Griffith Parkway
31.6 mi · 36 min · North Andy Griffith Parkway
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13
Keep slight right to continue on John Gold Memorial Expressway
9.2 mi · 11 min · John Gold Memorial Expressway
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14
Take the exit slight right toward US 311 North: Martin Luther King Jr Drive, Downtown
1038 ft · 28 sec
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15
Continue on North Research Parkway
1744 ft · 33 sec · North Research Parkway
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16
Turn right onto East 5th Street
1913 ft · 50 sec · East 5th Street
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17
Turn left onto North Main Street
20 m · 1 sec · North Main Street
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18
Arrive at your destination
0 m · 1 sec · North Main Street
Car Route Details
A richer read on the saved driving route between Greeneville and Winston-Salem.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Kingsport Highway
Merge slight left
106 mi · 01h 54m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms leaving Greeneville and Chance Showers And Thunderstorms near Winston-Salem.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greeneville to Winston-Salem?
The road trip is about 204.4 miles (328.9 km) and usually takes 03h 57m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Rural Retreat is a useful midpoint, sitting about 102.2 miles from Greeneville and 102.2 miles from Winston-Salem.
How much longer is the road route than the straight-line distance?
The direct path is about 144.4 miles (232.4 km), while the road route adds roughly 60 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 9:04 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $27.19 one way or $54.38 round trip. Estimated CO2 is about 64.1 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms then Slight Chance Showers And Thunderstorms around Greeneville and Chance Showers And Thunderstorms near Winston-Salem.
Stop Ideas Near Rural Retreat
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Rural Retreat.
Blacksburg, VA
Hinton
Alderson
Prince
Flight Path Map
This map shows the direct air route between Greeneville and Winston-Salem. Straight-line distance: 144.41 mi (232.41 km).
#1 Greeneville
Town in and county seat of Greene County, Tennessee, United States
| Population | 14,940 |
| Coordinates | 36.1631600, -82.8309900 |
| Altitude | 463 |
| Country | United States |
#2 Winston-Salem
The fifth most populous city in North Carolina.
| Population | 248,112 |
| Coordinates | 36.0998600, -80.2442200 |
| Altitude | 293 |
| Country | United States |
End: Winston-Salem (-80.24422, 36.09986)
Estimated Travel Time
Distance: 329 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 48m |
| 40 mph (64.37 km/h) | 05h 06m |
| 50 mph (80.47 km/h) | 04h 05m |
| 60 mph (96.56 km/h) | 03h 24m |
| 70 mph (112.65 km/h) | 02h 55m |
| 80 mph (129 km/h) | 02h 32m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $27.19 | $54.38 |
| Mid-grade | $4.25 | $30.66 | $61.33 |
| Premium | $4.65 | $33.56 | $67.11 |
| Diesel | $5.30 | $38.24 | $76.48 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Tennessee · Aug 03, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.