How far is Fredericktown, MO from Saint Joseph, MO?
The driving distance from Fredericktown, MO to Saint Joseph, MO is about 380.6 miles (612.5 km), with a travel time of about 05h 59m by car.
- The straight-line flight distance is about 289.1 miles (465.3 km).
- For a round trip, plan for roughly 11h 58m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 59m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The most populous city in the state of Missouri.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Fredericktown and Saint Joseph.
Turn-by-Turn Driving Directions
Step-by-step road directions between Fredericktown and Saint Joseph.
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1
Start on East Main Street
13 m · 3 sec · East Main Street
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2
Enter the roundabout and take exit 2 toward Court Square
82 m · 9 sec · West Main Street
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3
Exit the rotary onto West Main Street
1.2 mi · 3 min · West Main Street
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4
Enter the roundabout and take exit 3 toward the route
47 m · 3 sec
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5
Exit the roundabout
1755 ft · 39 sec
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6
Take the ramp right toward US 67 North: Farmington
1330 ft · 32 sec
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7
Merge slight left
51.6 mi · 59 min
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8
Keep slight right
1750 ft · 27 sec
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9
Take the exit straight toward I 55 North: Saint Louis
1735 ft · 49 sec
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10
Merge slight left
20.5 mi · 22 min
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11
Continue on Rosa Parks Highway
1.3 mi · 2 min · Rosa Parks Highway
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12
Take the exit slight right toward I 270 West, I 255 East: Kansas City, Chicago
1279 ft · 27 sec
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13
Keep slight left to continue on I 270 West: Kansas City
118 m · 8 sec
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14
Continue on I 270 West
1.2 km · 1 min
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15
Merge slight left
11.5 mi · 14 min
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16
Take the exit slight right toward I 64, US 40, US 61: Wentzville, Saint Louis
705 ft · 17 sec
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17
Keep slight left to continue on I 64 West, US 40 West, US 61 North: Wentzville
2009 ft · 49 sec
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18
Continue on I 64 West, US 40 West, US 61 North: Wentzville
674 ft · 10 sec
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19
Merge slight left onto Avenue of the Saints
25.4 mi · 31 min · Avenue of the Saints
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20
Take the exit slight left toward I 70 West, US 40 West: Kansas City
3047 ft · 1 min
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21
Merge slight left onto Dwight D Eisenhower Highway
80.7 mi · 1 hr 35 min · Dwight D Eisenhower Highway
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22
Continue on Sheriff Roger I. Wilson Memorial Highway
2 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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23
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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24
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
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25
Continue on U.S. Submarine Veterans' Memorial Highway
54.4 mi · 58 min · U.S. Submarine Veterans' Memorial Highway
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26
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
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27
Continue on Truman/Eisenhower Presidential Highway
2.7 mi · 3 min · Truman/Eisenhower Presidential Highway
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28
Continue on Clifton J. Scott Memorial Highway
1.8 mi · 2 min · Clifton J. Scott Memorial Highway
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29
Continue on Truman/Eisenhower Presidential Highway
2.9 mi · 3 min · Truman/Eisenhower Presidential Highway
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30
Continue on George Brett Super Highway
1.4 km · 58 sec · George Brett Super Highway
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31
Take the exit slight right toward I 435 North, US 24 East: Des Moines
1.1 mi · 2 min
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32
Merge slight left onto Lamar Hunt Memorial Highway
7.8 mi · 9 min · Lamar Hunt Memorial Highway
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33
Continue on I435 N
1.3 mi · 1 min · I435 N
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34
Continue straight
20.9 mi · 22 min
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35
Keep slight left to continue on I 29 North, US 71 North: Saint Joseph
26 mi · 28 min
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36
Take the exit slight right toward I 229 North: Downtown Saint Joseph
2673 ft · 54 sec
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37
Continue straight
5.7 mi · 7 min
-
38
Take the exit slight right toward Central Business District
1382 ft · 34 sec
-
39
Continue on Edmond Street
2408 ft · 58 sec · Edmond Street
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40
Turn left onto South 10th Street
841 ft · 21 sec · South 10th Street
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41
Turn right onto Frederick Avenue
116 m · 6 sec · Frederick Avenue
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42
Turn slight right onto Walter Welsh Avenue
42 m · 3 sec · Walter Welsh Avenue
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43
Arrive at your destination
0 m · 1 sec · Walter Welsh Avenue
Car Route Details
A richer read on the saved driving route between Fredericktown and Saint Joseph.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Dwight D Eisenhower Highway
Merge slight left onto Dwight D Eisenhower Highway
80.7 mi · 01h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Fredericktown and Sunny near Saint Joseph.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Fredericktown to Saint Joseph?
The road trip is about 380.6 miles (612.5 km) and usually takes 05h 59m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Columbia is a useful midpoint, sitting about 190.1 miles from Fredericktown and 190.5 miles from Saint Joseph.
How much longer is the road route than the straight-line distance?
The direct path is about 289.1 miles (465.3 km), while the road route adds roughly 91.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 5:02 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $50.64 one way or $101.29 round trip. Estimated CO2 is about 119.4 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Fredericktown and Sunny near Saint Joseph.
Stop Ideas Near Columbia
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Columbia.
Jefferson City
Sedalia
Hermann
Flight Path Map
This map shows the direct air route between Fredericktown and Saint Joseph. Straight-line distance: 289.11 mi (465.27 km).
#1 Fredericktown
City in and the county seat of Madison County, Missouri, United States
| Population | 4,005 |
| Coordinates | 37.5597800, -90.2940100 |
| Altitude | 226 |
| Country | United States |
#2 Saint Joseph
The most populous city in Buchanan County, Missouri.
| Population | 74,074 |
| Coordinates | 39.7686100, -94.8466300 |
| Altitude | 270 |
| Country | United States |
End: Walter Welsh Avenue (-94.846632, 39.768853)
Estimated Travel Time
Distance: 612 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 40m |
| 40 mph (64.37 km/h) | 09h 30m |
| 50 mph (80.47 km/h) | 07h 36m |
| 60 mph (96.56 km/h) | 06h 20m |
| 70 mph (112.65 km/h) | 05h 26m |
| 80 mph (129 km/h) | 04h 44m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $50.64 | $101.29 |
| Mid-grade | $4.25 | $57.12 | $114.24 |
| Premium | $4.65 | $62.50 | $125.01 |
| Diesel | $5.30 | $71.23 | $142.47 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 14, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.