How far is Florissant, MO from Kirksville, MO?
The driving distance from Florissant, MO to Kirksville, MO is about 198.1 miles (318.8 km), with a travel time of about 04h 01m by car.
- The straight-line flight distance is about 154.8 miles (249.1 km).
- For a round trip, plan for roughly 08h 02m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 01m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Ralls County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Florissant and Kirksville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Florissant and Kirksville.
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1
Start on North New Florissant Road
26 m · 6 sec · North New Florissant Road
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2
Turn right onto Washington Street
1 mi · 2 min · Washington Street
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3
Turn left onto Lindbergh Boulevard
1.7 mi · 3 min · Lindbergh Boulevard
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4
Take the ramp slight right
1912 ft · 47 sec
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5
Merge slight left onto Rosemary Straub Davison Highway
3.7 mi · 5 min · Rosemary Straub Davison Highway
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6
Take the exit slight right toward I 70: Saint Louis, Kansas City
1492 ft · 26 sec
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7
Continue on I 70: Saint Louis, Kansas City
2478 ft · 43 sec
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8
Keep slight right to continue on I 70 West: Kansas City
2439 ft · 42 sec
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9
Merge slight left
21.6 mi · 27 min
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10
Take the exit slight right toward US 61 North: Hannibal
2234 ft · 48 sec
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11
Merge slight left onto Avenue of the Saints
73.3 mi · 1 hr 27 min · Avenue of the Saints
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12
Take the exit slight left
76 m · 15 sec
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13
Turn left onto Paris Gravel Road
2645 ft · 1 min · Paris Gravel Road
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14
Keep slight right to continue on County Road 422
85 m · 9 sec · County Road 422
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15
Turn right onto Veterans Road
2.2 mi · 4 min · Veterans Road
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16
Take the ramp left toward US 36 West, MO 110 West: Monroe City
1226 ft · 16 sec
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17
Merge slight left onto V.F.W. Memorial Highway
5.8 mi · 7 min · V.F.W. Memorial Highway
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18
Continue on Chicago-Kansas City Expressway
52.9 mi · 1 hr 1 min · Chicago-Kansas City Expressway
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19
Take the exit slight right toward US 63: Macon, Kirksville
1054 ft · 29 sec
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20
Turn right onto North Missouri Street
28.5 mi · 32 min · North Missouri Street
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21
Take the exit slight right toward US 63 Business: Kirksville
1 km · 1 min
-
22
Continue on South Baltimore Street
1.6 mi · 2 min · South Baltimore Street
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23
Turn slight left onto Kirksville, Truman State University
76 m · 11 sec
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24
Continue on South Franklin Street
2 mi · 5 min · South Franklin Street
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25
Arrive at your destination
0 m · 1 sec · North Franklin Street
Car Route Details
A richer read on the saved driving route between Florissant and Kirksville.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Avenue of the Saints
Merge slight left onto Avenue of the Saints
73.3 mi · 01h 27m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Florissant and Sunny near Kirksville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Florissant to Kirksville?
The road trip is about 198.1 miles (318.8 km) and usually takes 04h 01m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Flint Hill is a useful midpoint, sitting about 99 miles from Florissant and 99.1 miles from Kirksville.
How much longer is the road route than the straight-line distance?
The direct path is about 154.8 miles (249.1 km), while the road route adds roughly 43.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:58 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $26.36 one way or $52.72 round trip. Estimated CO2 is about 62.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Florissant and Sunny near Kirksville.
Stop Ideas Near Flint Hill
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Flint Hill.
Quincy
Hermann
La Plata
Fort Madison station
Flight Path Map
This map shows the direct air route between Florissant and Kirksville. Straight-line distance: 154.78 mi (249.1 km).
#1 Florissant
The most populous city in St.
| Population | 50,795 |
| Coordinates | 38.7892200, -90.3226100 |
| Altitude | 175 |
| Country | United States |
#2 Kirksville
City in Adair County, Missouri, United States
| Population | 17,653 |
| Coordinates | 40.1947500, -92.5832500 |
| Altitude | 299 |
| Country | United States |
End: Kirksville (-92.58325, 40.19475)
Estimated Travel Time
Distance: 319 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 36m |
| 40 mph (64.37 km/h) | 04h 57m |
| 50 mph (80.47 km/h) | 03h 57m |
| 60 mph (96.56 km/h) | 03h 18m |
| 70 mph (112.65 km/h) | 02h 49m |
| 80 mph (129 km/h) | 02h 28m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $26.36 | $52.72 |
| Mid-grade | $4.25 | $29.73 | $59.46 |
| Premium | $4.65 | $32.53 | $65.06 |
| Diesel | $5.30 | $37.07 | $74.15 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Jun 03, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.