How far is East Independence, MO from Seneca, MO?
The driving distance from East Independence, MO to Seneca, MO is about 172.9 miles (278.2 km), with a travel time of about 03h 27m by car.
- The straight-line flight distance is about 156.3 miles (251.6 km).
- For a round trip, plan for roughly 06h 54m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 27m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Vernon County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between East Independence and Seneca.
Turn-by-Turn Driving Directions
Step-by-step road directions between East Independence and Seneca.
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1
Start on East 9th Street South
24 m · 9 sec · East 9th Street South
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2
Turn left onto Main Road
1341 ft · 1 min · Main Road
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3
Turn right onto East Truman Road
1.4 mi · 3 min · East Truman Road
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4
Take the ramp slight right toward MO 291 South: Lee's Summit
1589 ft · 43 sec
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5
Merge slight left
10 mi · 13 min
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6
Keep slight left to continue on MO 291 South: Harrisonville
3.3 mi · 6 min
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7
Take the ramp right toward US 50 West, MO 291 South: Kansas City
2959 ft · 54 sec
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8
Take the exit slight right toward MO 291 South: Jefferson Street, Harrisonville
767 ft · 19 sec
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9
Keep slight left to continue on MO 291 South: Harrisonville
16.9 mi · 25 min
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10
Continue on Cantrell Road
629 ft · 19 sec · Cantrell Road
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11
Take the exit straight toward I 49 South, US 71 South: Joplin
1138 ft · 28 sec
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12
Merge slight left
106.6 mi · 1 hr 54 min
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13
Take the exit slight right toward MO 571 South, MO 96, I 49 Business, MO 171 North: Webb City
706 ft · 15 sec
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14
Turn right onto Edward F. Dixon III Memorial Highway
6.6 mi · 7 min · Edward F. Dixon III Memorial Highway
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15
Keep slight left to continue on Governor Warren E Hearnes Memorial Highway
5.8 mi · 6 min · Governor Warren E Hearnes Memorial Highway
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16
Take the exit slight right toward I 44 West: Tulsa
1025 ft · 29 sec
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17
Merge slight left onto Congressman Gene Taylor Highway
1.1 mi · 1 min · Congressman Gene Taylor Highway
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18
Continue on George Washington Carver Memorial Highway
6.3 mi · 7 min · George Washington Carver Memorial Highway
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19
Take the exit slight right toward MO 43 South: Seneca
744 ft · 18 sec
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20
Keep slight left to continue on MO 43 South: Seneca
112 m · 13 sec
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21
Continue on Coyote Drive
2303 ft · 47 sec · Coyote Drive
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22
Continue on Cherokee Avenue
12.2 mi · 19 min · Cherokee Avenue
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23
Turn left onto Delaware Street
15 m · 2 sec · Delaware Street
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24
Arrive at your destination
0 m · 1 sec · Delaware Street
Car Route Details
A richer read on the saved driving route between East Independence and Seneca.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 49 South
Merge slight left
107 mi · 01h 54m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms leaving East Independence and Showers And Thunderstorms Likely near Seneca.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from East Independence to Seneca?
The road trip is about 172.9 miles (278.2 km) and usually takes 03h 27m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Nevada is a useful midpoint, sitting about 86.5 miles from East Independence and 86.3 miles from Seneca.
How much longer is the road route than the straight-line distance?
The direct path is about 156.3 miles (251.6 km), while the road route adds roughly 16.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:06 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $23.00 one way or $46.01 round trip. Estimated CO2 is about 54.2 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around East Independence and Showers And Thunderstorms Likely near Seneca.
Stop Ideas Near Nevada
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Nevada.
Warrensburg
Lee's Summit
Flight Path Map
This map shows the direct air route between East Independence and Seneca. Straight-line distance: 156.37 mi (251.65 km).
#1 East Independence
A census-designated place in Jackson County, Missouri.
| Population | 110,675 |
| Coordinates | 39.0955600, -94.3552300 |
| Altitude | 256 |
| Country | United States |
#2 Seneca
City in Missouri
| Population | 2,394 |
| Coordinates | 36.8414600, -94.6110600 |
| Altitude | 258 |
| Country | United States |
End: Seneca (-94.61106, 36.84146)
Estimated Travel Time
Distance: 278 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 45m |
| 40 mph (64.37 km/h) | 04h 19m |
| 50 mph (80.47 km/h) | 03h 27m |
| 60 mph (96.56 km/h) | 02h 52m |
| 70 mph (112.65 km/h) | 02h 28m |
| 80 mph (129 km/h) | 02h 09m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $23.00 | $46.01 |
| Mid-grade | $4.25 | $25.94 | $51.89 |
| Premium | $4.65 | $28.39 | $56.78 |
| Diesel | $5.30 | $32.35 | $64.71 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 30, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.