How far is East Independence, MO from Salem, MO?
The driving distance from East Independence, MO to Salem, MO is about 235.2 miles (378.5 km), with a travel time of about 04h 44m by car.
- The straight-line flight distance is about 182.6 miles (293.9 km).
- For a round trip, plan for roughly 09h 29m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 44m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The most populous city in the state of Missouri.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny then Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between East Independence and Salem.
Turn-by-Turn Driving Directions
Step-by-step road directions between East Independence and Salem.
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1
Start on East 9th Street South
24 m · 9 sec · East 9th Street South
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2
Turn left onto Main Road
1341 ft · 1 min · Main Road
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3
Turn left onto East Truman Road
1.1 km · 1 min · East Truman Road
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4
Turn right onto Holke Road
1.4 km · 2 min · Holke Road
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5
Turn straight onto South Jackson Drive
1.2 mi · 2 min · South Jackson Drive
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6
Turn left onto East R.D. Mize Road
1268 ft · 37 sec · East R.D. Mize Road
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7
Turn right onto South Little Blue Parkway
1.7 mi · 3 min · South Little Blue Parkway
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8
Take the ramp left toward Little Blue Parkway, 39th Street, Mall Entrance
1489 ft · 38 sec
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9
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
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10
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
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11
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22.4 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
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12
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
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13
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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14
Continue on Sheriff Roger I. Wilson Memorial Highway
1.5 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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15
Take the exit slight right toward US 63: Jefferson City, Moberly
748 ft · 16 sec
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16
Turn slight right onto US 63 South: Jefferson City
59 m · 4 sec
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17
Merge slight left
159 m · 12 sec
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18
Take the exit straight toward US 63 South: Jefferson City
2329 ft · 50 sec
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19
Merge slight left
27.1 mi · 29 min
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20
Take the exit slight right toward US 54 West, US 63 South: Jefferson City
1.5 mi · 2 min
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21
Take the exit slight right toward US 63 South, US 50
66 m · 5 sec
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22
Keep slight left to continue on US 63 South, US 50
724 ft · 16 sec
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23
Keep slight left to continue on US 63 South, US 50 East
547 ft · 15 sec
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24
Keep slight left
12 mi · 15 min
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25
Keep slight right to continue on US 63 South: Rolla
49.4 mi · 1 hr 4 min
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26
Turn left onto North Walnut Street
747 ft · 26 sec · North Walnut Street
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27
Continue on East 18th Street
1072 ft · 39 sec · East 18th Street
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28
Turn right onto Holloway Street
1.4 km · 3 min · Holloway Street
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29
At the end of the road, turn left onto Salem Avenue
1.2 km · 2 min · Salem Avenue
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30
Turn left
2.3 mi · 4 min
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31
Continue straight
21.2 mi · 27 min
-
32
Turn left
1.4 mi · 3 min
-
33
Turn left onto West 4th Street
1270 ft · 35 sec · West 4th Street
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34
Arrive at your destination
0 m · 1 sec · East 4th Street
Car Route Details
A richer read on the saved driving route between East Independence and Salem.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
52.5 mi · 00h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny then Slight Chance Showers And Thunderstorms leaving East Independence and Sunny near Salem.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from East Independence to Salem?
The road trip is about 235.2 miles (378.5 km) and usually takes 04h 44m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Columbia is a useful midpoint, sitting about 117.5 miles from East Independence and 117.7 miles from Salem.
How much longer is the road route than the straight-line distance?
The direct path is about 182.6 miles (293.9 km), while the road route adds roughly 52.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 7:30 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $31.30 one way or $62.60 round trip. Estimated CO2 is about 73.8 kg one way.
What should you check before leaving?
Before you leave, expect Sunny then Slight Chance Showers And Thunderstorms around East Independence and Sunny near Salem.
Stop Ideas Near Columbia
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Columbia.
Jefferson City
Sedalia
Hermann
Flight Path Map
This map shows the direct air route between East Independence and Salem. Straight-line distance: 182.63 mi (293.92 km).
#1 East Independence
A census-designated place in Jackson County, Missouri.
| Population | 110,675 |
| Coordinates | 39.0955600, -94.3552300 |
| Altitude | 256 |
| Country | United States |
#2 Salem
City in Missouri, United States
| Population | 4,874 |
| Coordinates | 37.6456000, -91.5359800 |
| Altitude | 361 |
| Country | United States |
End: Salem (-91.53598, 37.6456)
Estimated Travel Time
Distance: 379 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 50m |
| 40 mph (64.37 km/h) | 05h 52m |
| 50 mph (80.47 km/h) | 04h 42m |
| 60 mph (96.56 km/h) | 03h 55m |
| 70 mph (112.65 km/h) | 03h 21m |
| 80 mph (129 km/h) | 02h 56m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $31.30 | $62.60 |
| Mid-grade | $4.25 | $35.30 | $70.60 |
| Premium | $4.65 | $38.63 | $77.26 |
| Diesel | $5.30 | $44.02 | $88.05 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.