How far is East Independence, MO from Saint John, MO?
The driving distance from East Independence, MO to Saint John, MO is about 227.7 miles (366.4 km), with a travel time of about 04h 26m by car.
- The straight-line flight distance is about 217.1 miles (349.4 km).
- For a round trip, plan for roughly 08h 53m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 26m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
The most populous city in the state of Missouri.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Clear
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between East Independence and Saint John.
Turn-by-Turn Driving Directions
Step-by-step road directions between East Independence and Saint John.
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1
Start on East 9th Street South
24 m · 9 sec · East 9th Street South
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2
Turn left onto Main Road
1341 ft · 1 min · Main Road
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3
Turn left onto East Truman Road
1.1 km · 1 min · East Truman Road
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4
Turn right onto Holke Road
1.4 km · 2 min · Holke Road
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5
Turn straight onto South Jackson Drive
1.2 mi · 2 min · South Jackson Drive
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6
Turn left onto East R.D. Mize Road
1268 ft · 37 sec · East R.D. Mize Road
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7
Turn right onto South Little Blue Parkway
1.7 mi · 3 min · South Little Blue Parkway
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8
Take the ramp left toward Little Blue Parkway, 39th Street, Mall Entrance
1489 ft · 38 sec
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9
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
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10
Continue on U.S. Submarine Veterans' Memorial Highway
32 mi · 34 min · U.S. Submarine Veterans' Memorial Highway
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11
Keep slight left to continue on U.S. Submarine Veterans' Memorial Highway
22.4 mi · 24 min · U.S. Submarine Veterans' Memorial Highway
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12
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
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13
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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14
Continue on Sheriff Roger I. Wilson Memorial Highway
1.9 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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15
Continue on Dwight D. Eisenhower Highway
108.5 mi · 2 hr 9 min · Dwight D. Eisenhower Highway
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16
Take the exit slight right toward MO 115 East: Natural Bridge Road
942 ft · 25 sec
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17
Continue on Natural Bridge Road
1561 ft · 36 sec · Natural Bridge Road
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18
Turn right onto Brown Road
1.5 km · 2 min · Brown Road
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19
Turn left onto Saint Louis Avenue
560 ft · 27 sec · Saint Louis Avenue
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20
Turn right onto Marshall Road
66 m · 15 sec · Marshall Road
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21
Turn left onto Mavis Place
99 m · 14 sec · Mavis Place
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22
Arrive at your destination
0 m · 1 sec · Mavis Place
Car Route Details
A richer read on the saved driving route between East Independence and Saint John.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Dwight D. Eisenhower Highway
Continue on Dwight D. Eisenhower Highway
109 mi · 02h 09m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Clear leaving East Independence and Showers And Thunderstorms Likely near Saint John.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from East Independence to Saint John?
The road trip is about 227.7 miles (366.4 km) and usually takes 04h 26m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Columbia is a useful midpoint, sitting about 113.6 miles from East Independence and 114.1 miles from Saint John.
How much longer is the road route than the straight-line distance?
The direct path is about 217.1 miles (349.4 km), while the road route adds roughly 10.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:06 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $30.28 one way or $60.56 round trip. Estimated CO2 is about 71.4 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Clear around East Independence and Showers And Thunderstorms Likely near Saint John.
Stop Ideas Near Columbia
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Columbia.
Jefferson City
Sedalia
Hermann
Flight Path Map
This map shows the direct air route between East Independence and Saint John. Straight-line distance: 217.13 mi (349.44 km).
#1 East Independence
A census-designated place in Jackson County, Missouri.
| Population | 110,675 |
| Coordinates | 39.0955600, -94.3552300 |
| Altitude | 256 |
| Country | United States |
#2 Saint John
City in Missouri, USA
| Population | 6,319 |
| Coordinates | 38.7148400, -90.3462700 |
| Altitude | 196 |
| Country | United States |
End: Saint John (-90.34627, 38.71484)
Estimated Travel Time
Distance: 366 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 35m |
| 40 mph (64.37 km/h) | 05h 41m |
| 50 mph (80.47 km/h) | 04h 33m |
| 60 mph (96.56 km/h) | 03h 47m |
| 70 mph (112.65 km/h) | 03h 15m |
| 80 mph (129 km/h) | 02h 50m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $30.28 | $60.56 |
| Mid-grade | $4.25 | $34.15 | $68.30 |
| Premium | $4.65 | $37.37 | $74.74 |
| Diesel | $5.30 | $42.59 | $85.18 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 29, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.