How far is East Independence, MO from Doniphan, MO?
The driving distance from East Independence, MO to Doniphan, MO is about 351.7 miles (566 km), with a travel time of about 07h 12m by car.
- The straight-line flight distance is about 257.6 miles (414.5 km).
- For a round trip, plan for roughly 14h 25m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 12m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Christian County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between East Independence and Doniphan.
Turn-by-Turn Driving Directions
Step-by-step road directions between East Independence and Doniphan.
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1
Start on East 9th Street South
24 m · 9 sec · East 9th Street South
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2
Turn left onto Main Road
1341 ft · 1 min · Main Road
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3
Turn right onto East Truman Road
1.4 mi · 3 min · East Truman Road
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4
Take the ramp slight right toward MO 291 South: Lee's Summit
1589 ft · 43 sec
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5
Merge slight left
10 mi · 13 min
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6
Keep slight left to continue on MO 291 South: Harrisonville
3.3 mi · 6 min
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7
Take the ramp right toward US 50 West, MO 291 South: Kansas City
2959 ft · 54 sec
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8
Take the exit slight right toward MO 291 South: Jefferson Street, Harrisonville
767 ft · 19 sec
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9
Keep slight left to continue on MO 291 South: Harrisonville
16.9 mi · 25 min
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10
Continue on Cantrell Road
629 ft · 19 sec · Cantrell Road
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11
Take the exit straight toward I 49 South, US 71 South: Joplin
1138 ft · 28 sec
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12
Merge slight left
2.8 mi · 3 min
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13
Take the exit slight right toward MO 7 South: Clinton
924 ft · 20 sec
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14
Turn slight left onto MO 7 South: Clinton
55.5 mi · 1 hr 4 min
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15
Continue straight
68 mi · 1 hr 19 min
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16
Take the exit slight left toward I 44 East: Rolla, Saint Louis
954 ft · 23 sec
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17
Merge slight left onto Payne Stewart Highway
4.3 mi · 5 min · Payne Stewart Highway
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18
Take the exit slight right toward US 65 South: Branson
2343 ft · 50 sec
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19
Merge slight left onto Schoolcraft Freeway
8.3 mi · 10 min · Schoolcraft Freeway
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20
Take the exit slight right toward US 60 East: Cabool
1228 ft · 53 sec
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21
Merge slight left
82.2 mi · 1 hr 36 min
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22
Keep slight left to continue on US 60 East: Mountain View, Poplar Bluff
71.3 mi · 1 hr 24 min
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23
Turn right
24.3 mi · 36 min
-
24
Turn left onto Walnut Street
1.1 km · 1 min · Walnut Street
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25
Turn left onto Plum Street
52 m · 7 sec · Plum Street
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26
Arrive at your destination
0 m · 1 sec · Plum Street
Car Route Details
A richer read on the saved driving route between East Independence and Doniphan.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US 60 East
Merge slight left
82.2 mi · 01h 36m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Showers And Thunderstorms Likely leaving East Independence and Chance Showers And Thunderstorms near Doniphan.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from East Independence to Doniphan?
The road trip is about 351.7 miles (566 km) and usually takes 07h 12m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Fremont Hills is a useful midpoint, sitting about 175.8 miles from East Independence and 175.9 miles from Doniphan.
How much longer is the road route than the straight-line distance?
The direct path is about 257.6 miles (414.5 km), while the road route adds roughly 94.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.80 one way or $93.60 round trip. Estimated CO2 is about 110.3 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around East Independence and Chance Showers And Thunderstorms near Doniphan.
Stop Ideas Near Fremont Hills
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Historic City Hall
Nixa City Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Fremont Hills.
Flight Path Map
This map shows the direct air route between East Independence and Doniphan. Straight-line distance: 257.55 mi (414.49 km).
#1 East Independence
A census-designated place in Jackson County, Missouri.
| Population | 110,675 |
| Coordinates | 39.0955600, -94.3552300 |
| Altitude | 256 |
| Country | United States |
#2 Doniphan
City in Ripley County, Missouri, United States
| Population | 1,919 |
| Coordinates | 36.6208900, -90.8234600 |
| Altitude | 122 |
| Country | United States |
End: Doniphan (-90.82346, 36.62089)
Estimated Travel Time
Distance: 566 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 43m |
| 40 mph (64.37 km/h) | 08h 47m |
| 50 mph (80.47 km/h) | 07h 02m |
| 60 mph (96.56 km/h) | 05h 51m |
| 70 mph (112.65 km/h) | 05h 01m |
| 80 mph (129 km/h) | 04h 23m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $46.80 | $93.60 |
| Mid-grade | $4.25 | $52.78 | $105.56 |
| Premium | $4.65 | $57.76 | $115.51 |
| Diesel | $5.30 | $65.82 | $131.65 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.