How far is Des Plaines, IL from Saline, IL?
The driving distance from Des Plaines, IL to Saline, IL is about 350 miles (563.3 km), with a travel time of about 06h 52m by car.
- The straight-line flight distance is about 306.2 miles (492.8 km).
- For a round trip, plan for roughly 13h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 52m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Illinois
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Des Plaines and Saline.
Turn-by-Turn Driving Directions
Step-by-step road directions between Des Plaines and Saline.
-
1
Start on Henry Avenue
557 ft · 25 sec · Henry Avenue
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2
Turn right onto South Des Plaines River Road
1.8 mi · 3 min · South Des Plaines River Road
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3
Take the ramp slight right toward I 294 South: Indiana
2265 ft · 55 sec
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4
Merge slight left onto Tri-State Tollway
11.5 mi · 15 min · Tri-State Tollway
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5
Keep slight left to continue on Tri-State Tollway
4.8 mi · 6 min · Tri-State Tollway
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6
Keep slight right to continue on Tri-State Tollway
3.5 mi · 4 min · Tri-State Tollway
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7
Continue on Mile-Long Bridge
1.5 km · 1 min · Mile-Long Bridge
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8
Continue on Tri-State Tollway
8.5 mi · 11 min · Tri-State Tollway
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9
Take the exit slight right toward IL 50 South, IL 83: Cicero Avenue, 127th Street
1162 ft · 28 sec
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10
Keep slight left to continue on IL 50 South: Cicero Avenue
2529 ft · 1 min
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11
Turn straight onto Cicero Avenue
4.9 mi · 8 min · Cicero Avenue
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12
Turn left onto 167th Street
855 ft · 26 sec · 167th Street
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13
Take the ramp slight right toward I 57 South: Kankakee, I-80
3048 ft · 1 min
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14
Merge slight left
188.4 mi · 3 hr 24 min
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15
Keep slight left to continue on I 57 South: Memphis
65.7 mi · 1 hr 11 min
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16
Keep slight right to continue on Ken Gray Expressway
37.4 mi · 40 min · Ken Gray Expressway
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17
Take the exit slight right toward IL 13: Harrisburg, Marion, Carbondale
1758 ft · 43 sec
-
18
Keep slight left to continue on IL 13: Harrisburg, Marion, Carbondale
2421 ft · 59 sec
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19
Keep slight left
1102 ft · 29 sec
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20
Merge slight right onto West Deyoung Street
7.8 mi · 11 min · West Deyoung Street
-
21
Turn right onto Crab Orchard Road
1.4 km · 2 min · Crab Orchard Road
-
22
Turn right onto Saraville Road
3.7 mi · 9 min · Saraville Road
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23
Keep slight left to continue on Stonefort Road
5.1 mi · 12 min · Stonefort Road
-
24
Continue on Will Scarlet Road
1.3 mi · 5 min · Will Scarlet Road
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25
Turn left onto Peabody Road
1.2 km · 3 min · Peabody Road
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26
Arrive at your destination
0 m · 1 sec · Peabody Road
Car Route Details
A richer read on the saved driving route between Des Plaines and Saline.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 57 South
Merge slight left
188 mi · 03h 24m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny leaving Des Plaines and Sunny near Saline.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Des Plaines to Saline?
The road trip is about 350 miles (563.3 km) and usually takes 06h 52m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Tuscola is a useful midpoint, sitting about 175.1 miles from Des Plaines and 174.9 miles from Saline.
How much longer is the road route than the straight-line distance?
The direct path is about 306.2 miles (492.8 km), while the road route adds roughly 43.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $46.57 one way or $93.14 round trip. Estimated CO2 is about 109.8 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Des Plaines and Sunny near Saline.
Stop Ideas Near Tuscola
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Tuscola.
Illinois Terminal
Mattoon station
Rantoul
Danville, Illinois
Flight Path Map
This map shows the direct air route between Des Plaines and Saline. Straight-line distance: 306.23 mi (492.83 km).
#1 Des Plaines
The most populous city in Cook County, Illinois.
| Population | 58,179 |
| Coordinates | 42.0333600, -87.8834000 |
| Altitude | 193 |
| Country | United States |
#2 Saline
This southern Illinois community, with a population of approximately 23,182, is situated at an elevation of 400 feet in Saline County.
| Population | 23,182 |
| Coordinates | 37.6453300, -88.6958900 |
| Altitude | 122 |
| Country | United States |
End: Saline (-88.69589, 37.64533)
Estimated Travel Time
Distance: 563 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 39m |
| 40 mph (64.37 km/h) | 08h 45m |
| 50 mph (80.47 km/h) | 07h 00m |
| 60 mph (96.56 km/h) | 05h 50m |
| 70 mph (112.65 km/h) | 05h 00m |
| 80 mph (129 km/h) | 04h 21m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $46.57 | $93.14 |
| Mid-grade | $4.25 | $52.52 | $105.05 |
| Premium | $4.65 | $57.48 | $114.95 |
| Diesel | $5.30 | $65.50 | $131.01 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Illinois · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.