How far is De Kalb, TX from San Antonio, TX?
The driving distance from De Kalb, TX to San Antonio, TX is about 441.7 miles (710.9 km), with a travel time of about 06h 49m by car.
- The straight-line flight distance is about 363.1 miles (584.3 km).
- For a round trip, plan for roughly 13h 38m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 49m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in the U.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between De Kalb and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between De Kalb and San Antonio.
-
1
Start on Northeast Front Street
10 m · 8 sec · Northeast Front Street
-
2
Turn left onto South Runnels Street
2.4 mi · 4 min · South Runnels Street
-
3
At the end of the road, turn right
44 m · 8 sec
-
4
Turn left onto US Highway 259 South
13.9 mi · 21 min · US Highway 259 South
-
5
Take the ramp right
2301 ft · 56 sec
-
6
Merge slight left
131.8 mi · 2 hr 17 min
-
7
Take the exit slight right toward I 35E: Denton, Waco
3065 ft · 1 min
-
8
Keep slight left to continue on I 35E South, I 35E North: Waco, Denton
607 ft · 15 sec
-
9
Keep slight left to continue on I 35E North, I 35E South: Denton, Waco
67 m · 5 sec
-
10
Keep slight left to continue on I 35E South: Waco
1915 ft · 30 sec
-
11
Continue on South R L Thornton Freeway
2866 ft · 44 sec · South R L Thornton Freeway
-
12
Continue on South R L Thornton Freeway
89.3 mi · 1 hr 32 min · South R L Thornton Freeway
-
13
Continue on North Jack Kultgen Expressway
6.6 mi · 8 min · North Jack Kultgen Expressway
-
14
Continue on Purple Heart Trail
37.9 mi · 39 min · Purple Heart Trail
-
15
Keep slight left
55.8 mi · 59 min
-
16
Keep slight left to continue on Purple Heart Trail
49.8 mi · 55 min · Purple Heart Trail
-
17
Continue on Interstate Highway 35
1.7 mi · 2 min · Interstate Highway 35
-
18
Continue on Purple Heart Trail
11.9 mi · 13 min · Purple Heart Trail
-
19
Continue on North Pan Am Expressway
10 mi · 12 min · North Pan Am Expressway
-
20
Keep slight left to continue on North Pan Am Expressway
6.4 mi · 8 min · North Pan Am Expressway
-
21
Keep slight left to continue on North Pan Am Expressway
2907 ft · 41 sec · North Pan Am Expressway
-
22
Take the exit slight right toward Lexington Avenue, Main Avenue, San Pedro Avenue
684 ft · 17 sec
-
23
Turn straight onto East Elmira Street
526 ft · 17 sec · East Elmira Street
-
24
Turn left onto North Main Avenue
830 ft · 19 sec · North Main Avenue
-
25
Enter the roundabout and take exit 2 toward Navarro Street
49 m · 3 sec · Navarro Street
-
26
Exit the roundabout onto Navarro Street
34 m · 2 sec · Navarro Street
-
27
Keep slight right to continue on North Main Avenue
2181 ft · 52 sec · North Main Avenue
-
28
Turn right onto West Travis Street
68 m · 11 sec · West Travis Street
-
29
Turn left onto North Flores Street
807 ft · 20 sec · North Flores Street
-
30
Continue on Military Plaza
119 m · 16 sec · Military Plaza
-
31
Turn left onto Dolorosa Street
100 m · 8 sec · Dolorosa Street
-
32
Arrive at your destination
0 m · 1 sec · Dolorosa Street
Car Route Details
A richer read on the saved driving route between De Kalb and San Antonio.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US Highway 259 South
Merge slight left
132 mi · 02h 17m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Sunny leaving De Kalb and Mostly Sunny near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from De Kalb to San Antonio?
The road trip is about 441.7 miles (710.9 km) and usually takes 06h 49m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Hillsboro is a useful midpoint, sitting about 210.9 miles from De Kalb and 230.8 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 363.1 miles (584.3 km), while the road route adds roughly 78.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $58.91 one way or $117.83 round trip. Estimated CO2 is about 138.5 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around De Kalb and Mostly Sunny near San Antonio.
Stop Ideas Near Hillsboro
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Historic City Hall
Whitney City Hall
Town Hall Estates Nursing
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Hillsboro.
Cleburne
Waco, TX
McGregor
Fort Worth Central Station
Flight Path Map
This map shows the direct air route between De Kalb and San Antonio. Straight-line distance: 363.05 mi (584.28 km).
#1 De Kalb
Town in Mississippi, United States
| Population | 1,611 |
| Coordinates | 33.5087300, -94.6163200 |
| Altitude | 125 |
| Country | United States |
#2 San Antonio
The seventh most populous city in the United States and the center of the San Antonio metropolitan area.
| Population | 1,567,118 |
| Coordinates | 29.4241200, -98.4936300 |
| Altitude | 198 |
| Country | United States |
End: Dolorosa Street (-98.493645, 29.424163)
Estimated Travel Time
Distance: 711 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 14h 43m |
| 40 mph (64.37 km/h) | 11h 02m |
| 50 mph (80.47 km/h) | 08h 50m |
| 60 mph (96.56 km/h) | 07h 21m |
| 70 mph (112.65 km/h) | 06h 18m |
| 80 mph (129 km/h) | 05h 30m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $58.91 | $117.83 |
| Mid-grade | $4.25 | $66.29 | $132.58 |
| Premium | $4.59 | $71.57 | $143.15 |
| Diesel | $3.99 | $62.25 | $124.50 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · May 12, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.