How far is Carthage, MS from Biloxi, MS?
Fastest route
The route from Carthage, Mississippi 39051 to Biloxi, Mississippi is approximately 187 miles and takes about 3 hours and 7 minutes via MS-35 S and US 49 S. The fastest route is recommended due to traffic conditions.
Directions
- Head south on MS-35 S toward MS-16 W.
- Continue straight to stay on MS-35 S. Pass by Trustmark (on the left in 22.5 mi).
- Turn right onto MS-28 W/MS-35 S.
- Turn left onto MS-35 S/Oak St. Continue to follow MS-35 S.
- Turn right to stay on S Main St.
- Continue on US 49 S. Take MS-67 S to Division St in Biloxi. Take exit 1C from I-110.
- Take Caillavet St and Esters Blvd to Howard Ave.
Tips & Suggestions
- 🛣️ Follow the fastest route via MS-35 S and US 49 S to reach Biloxi.
- ⏰ Consider checking traffic conditions before starting your journey.
- 🚗 Ensure your vehicle is in good condition and has enough fuel for the trip.
- 🗺️ Use a GPS or navigation app to stay on track and navigate through the route.
- 🚦 Observe traffic rules and regulations during the journey.
- 📱 Keep your mobile phone charged and easily accessible for any emergency situations.
- 🛣️ Enjoy the scenic drive and have a safe trip!
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 46m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Pike County, Mississippi, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Carthage and Biloxi.
Turn-by-Turn Driving Directions
Step-by-step road directions between Carthage and Biloxi.
-
1
Start on the route
14 m · 2 sec
-
2
Turn straight onto Carthage Point Road
2.1 mi · 8 min · Carthage Point Road
-
3
Keep slight left to continue on Carthage Point Road
668 ft · 29 sec · Carthage Point Road
-
4
Turn straight onto Lower Woodville Road
1.3 km · 2 min · Lower Woodville Road
-
5
Turn right onto Highland Boulevard
1 mi · 3 min · Highland Boulevard
-
6
Turn left onto Seargent Prentiss Drive
6.4 mi · 8 min · Seargent Prentiss Drive
-
7
Take the exit slight right
28.3 mi · 33 min
-
8
Take the exit slight right
1435 ft · 39 sec
-
9
Keep slight left
51 m · 5 sec
-
10
Turn right
3187 ft · 44 sec
-
11
Turn right
28.9 mi · 33 min
-
12
Take the exit slight right
13.6 mi · 15 min
-
13
Continue straight
43.2 mi · 46 min
-
14
Take the exit slight right toward I 12 East: Slidell
1124 ft · 28 sec
-
15
Merge slight left onto West Florida Republic Parkway
47.5 mi · 51 min · West Florida Republic Parkway
-
16
Continue on West Florida Republic Parkway
1.1 km · 44 sec · West Florida Republic Parkway
-
17
Merge slight left onto Stephen E Ambrose Memorial Parkway
51.2 mi · 55 min · Stephen E Ambrose Memorial Parkway
-
18
Take the exit slight right toward I 110, MS 15, MS 67: Biloxi, Keesler Air Force Base
605 ft · 15 sec
-
19
Keep slight left
2126 ft · 52 sec
-
20
Keep slight right to continue on I 110: Biloxi, Keesler Air Force Base
2830 ft · 1 min
-
21
Merge slight left
2.7 mi · 4 min
-
22
Take the exit slight right toward Division Street
1852 ft · 47 sec
-
23
Turn left onto Division Street
3090 ft · 2 min · Division Street
-
24
Turn right onto Main Street
2572 ft · 1 min · Main Street
-
25
Turn left onto Howard Avenue
28 m · 3 sec · Howard Avenue
-
26
Arrive at your destination
0 m · 1 sec · Howard Avenue
Car Route Details
A richer read on the saved driving route between Carthage and Biloxi.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Stephen E Ambrose Memorial Parkway
Merge slight left onto Stephen E Ambrose Memorial Parkway
51.2 mi · 00h 55m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Carthage and Sunny near Biloxi.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Carthage to Biloxi?
The road trip is about 211.5 miles (340.4 km) and usually takes 03h 46m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Osyka is a useful midpoint, sitting about 115.1 miles from Carthage and 96.4 miles from Biloxi.
How much longer is the road route than the straight-line distance?
The direct path is about 170.6 miles (274.6 km), while the road route adds roughly 40.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:28 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $28.29 one way or $56.58 round trip. Estimated CO2 is about 66.4 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Carthage and Sunny near Biloxi.
Stop Ideas Near Osyka
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Osyka.
McComb
Hammond
Brookhaven
Baton Rouge, Louisiana
Flight Path Map
This map shows the direct air route between Carthage and Biloxi. Straight-line distance: 170.63 mi (274.61 km).
#1 Carthage
Human settlement in Leake County, Mississippi, United States of America
| Population | 4,725 |
| Coordinates | 31.5265600, -91.4459500 |
| Altitude | 22 |
| Country | United States |
#2 Biloxi
The most populous city in Harrison County, Mississippi.
| Population | 46,127 |
| Coordinates | 30.3960300, -88.8853100 |
| Altitude | 6 |
| Country | United States |
End: Howard Avenue (-88.885301, 30.396075)
Estimated Travel Time
Distance: 340 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 02m |
| 40 mph (64.37 km/h) | 05h 17m |
| 50 mph (80.47 km/h) | 04h 13m |
| 60 mph (96.56 km/h) | 03h 31m |
| 70 mph (112.65 km/h) | 03h 01m |
| 80 mph (129 km/h) | 02h 38m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.79 | $28.29 | $56.58 |
| Mid-grade | $4.26 | $31.81 | $63.63 |
| Premium | $4.63 | $34.55 | $69.10 |
| Diesel | $5.42 | $40.45 | $80.90 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Mississippi · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.