How far is Amherst, NY from Cairo, NY?
The driving distance from Amherst, NY to Cairo, NY is about 288.5 miles (464.3 km), with a travel time of about 05h 55m by car.
- The straight-line flight distance is about 248.5 miles (399.9 km).
- For a round trip, plan for roughly 11h 50m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 55m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census-designated place in Onondaga County, New York
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Amherst and Cairo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Amherst and Cairo.
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1
Start on Millersport Highway
1848 ft · 51 sec · Millersport Highway
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2
Take the ramp slight right toward I 290 E
1756 ft · 43 sec
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3
Merge slight left onto Youngmann Expressway
2.4 mi · 3 min · Youngmann Expressway
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4
Keep slight left to continue on I 90 East: Albany
1 km · 57 sec
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5
Merge slight left onto New York State Thruway
225.6 mi · 4 hr 21 min · New York State Thruway
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6
Take the exit slight right toward NY 10: Canajoharie, Sharon Springs
2504 ft · 1 min
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7
At the end of the road, turn left onto East Main Street
1236 ft · 27 sec · East Main Street
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8
Continue on State Highway 5S
2.2 mi · 3 min · State Highway 5S
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9
Keep slight right
15.1 mi · 21 min
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10
Turn left onto Junction Road
1.3 mi · 2 min · Junction Road
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11
Continue on Zicha Road
1.1 mi · 2 min · Zicha Road
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12
Continue on State Highway 30A
2.5 mi · 4 min · State Highway 30A
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13
Continue on North Main Street
2.3 mi · 5 min · North Main Street
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14
Continue on State Highway 30
3.3 mi · 5 min · State Highway 30
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15
Continue on River Street
3253 ft · 58 sec · River Street
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16
At the end of the road, turn left onto Main Street
1.1 mi · 3 min · Main Street
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17
Continue on State Highway 145
27.6 mi · 40 min · State Highway 145
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18
Turn straight onto State Highway 23
2180 ft · 36 sec · State Highway 23
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19
Turn right onto County Road 85
541 ft · 16 sec · County Road 85
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20
Turn left
72 m · 7 sec
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21
Continue on Jerome Avenue
1715 ft · 47 sec · Jerome Avenue
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22
Turn slight left onto Main Street
1396 ft · 40 sec · Main Street
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23
Arrive at your destination
0 m · 1 sec · Main Street
Car Route Details
A richer read on the saved driving route between Amherst and Cairo.
Straightforward drive
The saved road route has a manageable number of maneuvers and should be easy to follow with normal attention to signs.
New York State Thruway
Merge slight left onto New York State Thruway
226 mi · 04h 21m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Amherst and Mostly Sunny near Cairo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Amherst to Cairo?
The road trip is about 288.5 miles (464.3 km) and usually takes 05h 55m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Lyncourt is a useful midpoint, sitting about 144 miles from Amherst and 144.5 miles from Cairo.
How much longer is the road route than the straight-line distance?
The direct path is about 248.5 miles (399.9 km), while the road route adds roughly 40 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 5:10 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $40.81 one way or $81.62 round trip. Estimated CO2 is about 90.5 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Amherst and Mostly Sunny near Cairo.
Stop Ideas Near Lyncourt
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
City Hall Cafe
Syracuse City Hall
Town hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lyncourt.
William F. Walsh Regional Transportation Center
Empire Expo Center
Rome station
Union Station
Flight Path Map
This map shows the direct air route between Amherst and Cairo. Straight-line distance: 248.47 mi (399.88 km).
#1 Amherst
Town in New York, United States
| Population | 120,809 |
| Coordinates | 42.9783900, -78.7997600 |
| Altitude | 182 |
| Country | United States |
#2 Cairo
Town in Greene County, New York, United States
| Population | 6,420 |
| Coordinates | 42.2989700, -73.9984700 |
| Altitude | 114 |
| Country | United States |
End: Cairo (-73.99847, 42.29897)
Estimated Travel Time
Distance: 464 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 36m |
| 40 mph (64.37 km/h) | 07h 12m |
| 50 mph (80.47 km/h) | 05h 46m |
| 60 mph (96.56 km/h) | 04h 48m |
| 70 mph (112.65 km/h) | 04h 07m |
| 80 mph (129 km/h) | 03h 35m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.01 | $40.81 | $81.62 |
| Mid-grade | $4.48 | $45.62 | $91.23 |
| Premium | $4.86 | $49.48 | $98.97 |
| Diesel | $4.69 | $47.78 | $95.57 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in New York · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.