How far is Affton, MO from Cape Girardeau, MO?
The driving distance from Affton, MO to Cape Girardeau, MO is about 111.2 miles (179 km), with a travel time of about 01h 45m by car.
- The straight-line flight distance is about 96.8 miles (155.8 km).
- For a round trip, plan for roughly 03h 30m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 45m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in and the county seat of Ste.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Affton and Cape Girardeau.
Turn-by-Turn Driving Directions
Step-by-step road directions between Affton and Cape Girardeau.
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1
Start on the route
36 m · 16 sec
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2
Turn left onto Tesson Ferry Road
2427 ft · 1 min · Tesson Ferry Road
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3
Turn left onto Reavis Road
2749 ft · 1 min · Reavis Road
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4
Turn right onto Mackenzie Road
2623 ft · 1 min · Mackenzie Road
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5
Turn straight onto Reavis Barracks Road
1.1 km · 1 min · Reavis Barracks Road
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6
Take the ramp slight right toward I 55 South
997 ft · 14 sec
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7
Merge slight left
99.2 mi · 1 hr 47 min
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8
Take the exit slight right toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson
814 ft · 17 sec
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9
Keep slight left to continue on I 55 Business, US 61 South, MO 34 East: Cape Girardeau
1354 ft · 29 sec
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10
Continue on North Kingshighway
3.6 mi · 6 min · North Kingshighway
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11
Turn left onto Broadway Street
2 mi · 4 min · Broadway Street
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12
Arrive at your destination
0 m · 1 sec · Broadway Street
Car Route Details
A richer read on the saved driving route between Affton and Cape Girardeau.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 South
Merge slight left
99.2 mi · 01h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Showers And Thunderstorms leaving Affton and Showers And Thunderstorms near Cape Girardeau.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Affton to Cape Girardeau?
The road trip is about 111.2 miles (179 km) and usually takes 01h 45m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Sainte Genevieve is a useful midpoint, sitting about 53.9 miles from Affton and 57.4 miles from Cape Girardeau.
How much longer is the road route than the straight-line distance?
The direct path is about 96.8 miles (155.8 km), while the road route adds roughly 14.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 3:00 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $14.82 one way or $29.64 round trip. Estimated CO2 is about 34.9 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms around Affton and Showers And Thunderstorms near Cape Girardeau.
Stop Ideas Near Sainte Genevieve
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Sainte Genevieve.
Du Quoin
Gateway Transportation Center
Kirkwood
Carbondale station
Flight Path Map
This map shows the direct air route between Affton and Cape Girardeau. Straight-line distance: 96.8 mi (155.78 km).
#1 Affton
Census designated place
| Population | 20,307 |
| Coordinates | 38.5506100, -90.3331700 |
| Altitude | 188 |
| Country | United States |
#2 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
End: Broadway Street (-89.518146, 37.305904)
Estimated Travel Time
Distance: 179 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 42m |
| 40 mph (64.37 km/h) | 02h 46m |
| 50 mph (80.47 km/h) | 02h 13m |
| 60 mph (96.56 km/h) | 01h 51m |
| 70 mph (112.65 km/h) | 01h 35m |
| 80 mph (129 km/h) | 01h 23m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $14.82 | $29.64 |
| Mid-grade | $4.25 | $16.71 | $33.43 |
| Premium | $4.65 | $18.29 | $36.58 |
| Diesel | $5.30 | $20.84 | $41.69 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 24, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.