How far is Holly Springs, NC from Winston-Salem, NC?
The driving distance from Holly Springs, NC to Winston-Salem, NC is about 99.5 miles (160.2 km), with a travel time of about 01h 41m by car.
- The straight-line flight distance is about 84.8 miles (136.5 km).
- For a round trip, plan for roughly 03h 22m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 41m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in North Carolina
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Partly Sunny
Driving Route Map
The map below follows the saved road route between Holly Springs and Winston-Salem.
Turn-by-Turn Driving Directions
Step-by-step road directions between Holly Springs and Winston-Salem.
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1
Start on North Main Street
2 mi · 4 min · North Main Street
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2
Continue on East Williams Street
1406 ft · 31 sec · East Williams Street
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3
Turn left onto Old Smithfield Road
2261 ft · 57 sec · Old Smithfield Road
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4
Merge slight left
1720 ft · 28 sec
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5
Take the exit slight right toward NC 540 Toll West
1099 ft · 27 sec
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6
Merge slight left onto Triangle Expressway
5.3 mi · 6 min · Triangle Expressway
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7
Take the exit slight right toward US 64: Apex, Pittsboro
1111 ft · 27 sec
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8
Keep slight left
1902 ft · 46 sec
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9
Keep slight right to continue on US 64 West: Pittsboro
1274 ft · 31 sec
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10
Merge slight left
32 mi · 42 min
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11
Take the exit right
1943 ft · 47 sec
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12
Merge slight left onto Isaac Brooks Highway
25.5 mi · 31 min · Isaac Brooks Highway
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13
Take the exit slight right toward I 85, US 421 North: Winston-Salem, Durham, Charlotte
1107 ft · 27 sec
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14
Keep slight left to continue on I 85 South, US 421 North: Winston-Salem, Charlotte
1.3 km · 2 min
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15
Merge slight left onto Greensboro Urban Loop
4.8 mi · 5 min · Greensboro Urban Loop
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16
Keep slight right to continue on Greensboro Urban Loop
6.7 mi · 7 min · Greensboro Urban Loop
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17
Keep slight left to continue on I 40 West, US 421 North: Winston-Salem
5.8 mi · 7 min
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18
Keep slight right to continue on Salem Parkway
13.4 mi · 16 min · Salem Parkway
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19
Take the exit slight right toward Main Street
1174 ft · 29 sec
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20
Turn slight right onto South Main Street
2161 ft · 44 sec · South Main Street
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21
Arrive at your destination
0 m · 1 sec · North Main Street
Car Route Details
A richer read on the saved driving route between Holly Springs and Winston-Salem.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US 64 West
Merge slight left
32 mi · 00h 42m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny leaving Holly Springs and Partly Sunny near Winston-Salem.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Holly Springs to Winston-Salem?
The road trip is about 99.5 miles (160.2 km) and usually takes 01h 41m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Staley is a useful midpoint, sitting about 49.8 miles from Holly Springs and 49.8 miles from Winston-Salem.
How much longer is the road route than the straight-line distance?
The direct path is about 84.8 miles (136.5 km), while the road route adds roughly 14.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 3:08 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $13.90 one way or $27.81 round trip. Estimated CO2 is about 31.2 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Holly Springs and Partly Sunny near Winston-Salem.
Stop Ideas Near Staley
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Staley.
Burlington
J. Douglas Galyon Depot
High Point
Durham
Flight Path Map
This map shows the direct air route between Holly Springs and Winston-Salem. Straight-line distance: 84.84 mi (136.53 km).
#1 Holly Springs
City in and county seat of Marshall County, Mississippi, United States
| Population | 31,377 |
| Coordinates | 35.6512700, -78.8336200 |
| Altitude | 134 |
| Country | United States |
#2 Winston-Salem
The fifth most populous city in North Carolina.
| Population | 248,112 |
| Coordinates | 36.0998600, -80.2442200 |
| Altitude | 293 |
| Country | United States |
End: North Main Street (-80.244255, 36.099856)
Estimated Travel Time
Distance: 160 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 19m |
| 40 mph (64.37 km/h) | 02h 29m |
| 50 mph (80.47 km/h) | 01h 59m |
| 60 mph (96.56 km/h) | 01h 39m |
| 70 mph (112.65 km/h) | 01h 25m |
| 80 mph (129 km/h) | 01h 14m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $13.90 | $27.81 |
| Mid-grade | $4.43 | $15.55 | $31.09 |
| Premium | $4.78 | $16.77 | $33.54 |
| Diesel | $5.62 | $19.74 | $39.48 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in North Carolina · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.